Liver Disease and Cancer

Genetic and Environmental Risk of Liver Disease/Cancer Among Mexicans

The main objective of this study was to investigate the association between 288 SNPs identified in genome-wide association studies and risk of elevated transaminase levels in an admixed Mexican-Mestizo sample of 178 cases of NAFLD and 454 healthy controls. The results of this study suggest that among Mexicans, the PNPLA3 (rs738409), LYPLAL1 (rs12137855), PPP1R3B (rs4240624), and GCKR (rs780094) polymorphisms may be […]

Understanding and Addressing Disparities in Liver Cancer Prevention and Control

We compare the prevalence of risk factors and receipt of clinical procedures (HBV/HCV, alcohol, obesity, diabetes, elevated liver enzyme tests, etc.) as well as socio-demographic characteristics (age, sex, race/ethnicity) in patients with and without chronic liver disease (NALFD, NASH, cirrhosis, HCC). Additionally, we assess adherence to best practices for management and surveillance among specific high-risk […]